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Application of an F0-based genetic assay in adult zebrafish to identify modifier genes of an inherited cardiomyopathy

Modifier genes contribute significantly to our understanding of pathophysiology in human diseases; however, effective approaches to identify modifier genes are still lacking. Here, we aim to develop a rapid F0-based genetic assay in adult zebrafish using the bag3 gene knockout (bag3(e2/e2)) cardiomy...

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Detalles Bibliográficos
Autores principales: Ding, Yonghe, Wang, Mingmin, Bu, Haisong, Li, Jiarong, Lin, Xueying, Xu, Xiaolei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239171/
https://www.ncbi.nlm.nih.gov/pubmed/35481478
http://dx.doi.org/10.1242/dmm.049427