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Mycobacterium tuberculosis PPE51 Inhibits Autophagy by Suppressing Toll-Like Receptor 2-Dependent Signaling

Autophagy is an ubiquitous homeostatic pathway in mammalian cells and plays a significant role in host immunity. Substantial evidence indicates that the ability of Mycobacterium tuberculosis (Mtb) to successfully evade immune responses is partially due to inhibition of autophagic pathways. Our previ...

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Detalles Bibliográficos
Autores principales: Strong, Emily J., Wang, Jia, Ng, Tony W., Porcelli, Steven A., Lee, Sunhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239179/
https://www.ncbi.nlm.nih.gov/pubmed/35467412
http://dx.doi.org/10.1128/mbio.02974-21