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Aminoglycoside Antibiotics Inhibit Phage Infection by Blocking an Early Step of the Infection Cycle

In response to viral predation, bacteria have evolved a wide range of defense mechanisms, which rely mostly on proteins acting at the cellular level. Here, we show that aminoglycosides, a well-known class of antibiotics produced by Streptomyces, are potent inhibitors of phage infection in widely div...

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Detalles Bibliográficos
Autores principales: Kever, Larissa, Hardy, Aël, Luthe, Tom, Hünnefeld, Max, Gätgens, Cornelia, Milke, Lars, Wiechert, Johanna, Wittmann, Johannes, Moraru, Cristina, Marienhagen, Jan, Frunzke, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239200/
https://www.ncbi.nlm.nih.gov/pubmed/35506667
http://dx.doi.org/10.1128/mbio.00783-22