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The Shigella Spp. Type III Effector Protein OspB Is a Cysteine Protease

The type III secretion system is required for virulence of many pathogenic bacteria. Bacterial effector proteins delivered into target host cells by this system modulate host signaling pathways and processes in a manner that promotes infection. Here, we define the activity of the effector protein Os...

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Detalles Bibliográficos
Autores principales: Wood, Thomas E., Westervelt, Kathleen A., Yoon, Jessica M., Eshleman, Heather D., Levy, Roie, Burnes, Henry, Slade, Daniel J., Lesser, Cammie F., Goldberg, Marcia B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239218/
https://www.ncbi.nlm.nih.gov/pubmed/35638611
http://dx.doi.org/10.1128/mbio.01270-22