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A Silent Operon of Photorhabdus luminescens Encodes a Prodrug Mimic of GTP

With the overmining of actinomycetes for compounds acting against Gram-negative pathogens, recent efforts to discover novel antibiotics have been focused on other groups of bacteria. Teixobactin, the first antibiotic without detectable resistance that binds lipid II, comes from an uncultured Elefthe...

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Detalles Bibliográficos
Autores principales: Shahsavari, Negar, Wang, Boyuan, Imai, Yu, Mori, Miho, Son, Sangkeun, Liang, Libang, Böhringer, Nils, Manuse, Sylvie, Gates, Michael F., Morrissette, Madeleine, Corsetti, Rachel, Espinoza, Josh L., Dupont, Chris L., Laub, Michael T., Lewis, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239236/
https://www.ncbi.nlm.nih.gov/pubmed/35575547
http://dx.doi.org/10.1128/mbio.00700-22