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A Silent Operon of Photorhabdus luminescens Encodes a Prodrug Mimic of GTP
With the overmining of actinomycetes for compounds acting against Gram-negative pathogens, recent efforts to discover novel antibiotics have been focused on other groups of bacteria. Teixobactin, the first antibiotic without detectable resistance that binds lipid II, comes from an uncultured Elefthe...
Autores principales: | Shahsavari, Negar, Wang, Boyuan, Imai, Yu, Mori, Miho, Son, Sangkeun, Liang, Libang, Böhringer, Nils, Manuse, Sylvie, Gates, Michael F., Morrissette, Madeleine, Corsetti, Rachel, Espinoza, Josh L., Dupont, Chris L., Laub, Michael T., Lewis, Kim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239236/ https://www.ncbi.nlm.nih.gov/pubmed/35575547 http://dx.doi.org/10.1128/mbio.00700-22 |
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