Proteolytic Activity-Independent Activation of the Immune Response by Gingipains from Porphyromonas gingivalis

Porphyromonas gingivalis, a keystone pathogen in periodontitis (PD), produces cysteine proteases named gingipains (RgpA, RgpB, and Kgp), which strongly affect the host immune system. The range of action of gingipains is extended by their release as components of outer membrane vesicles, which effici...

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Detalles Bibliográficos
Autores principales: Ciaston, Izabela, Budziaszek, Joanna, Satala, Dorota, Potempa, Barbara, Fuchs, Andrew, Rapala-Kozik, Maria, Mizgalska, Danuta, Dobosz, Ewelina, Lamont, Richard J., Potempa, Jan, Koziel, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239244/
https://www.ncbi.nlm.nih.gov/pubmed/35491845
http://dx.doi.org/10.1128/mbio.03787-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239244/
https://www.ncbi.nlm.nih.gov/pubmed/35491845
http://dx.doi.org/10.1128/mbio.03787-21

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