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Proteolytic Activity-Independent Activation of the Immune Response by Gingipains from Porphyromonas gingivalis
Porphyromonas gingivalis, a keystone pathogen in periodontitis (PD), produces cysteine proteases named gingipains (RgpA, RgpB, and Kgp), which strongly affect the host immune system. The range of action of gingipains is extended by their release as components of outer membrane vesicles, which effici...
Autores principales: | Ciaston, Izabela, Budziaszek, Joanna, Satala, Dorota, Potempa, Barbara, Fuchs, Andrew, Rapala-Kozik, Maria, Mizgalska, Danuta, Dobosz, Ewelina, Lamont, Richard J., Potempa, Jan, Koziel, Joanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239244/ https://www.ncbi.nlm.nih.gov/pubmed/35491845 http://dx.doi.org/10.1128/mbio.03787-21 |
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