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The Leishmania donovani Ortholog of the Glycosylphosphatidylinositol Anchor Biosynthesis Cofactor PBN1 Is Essential for Host Infection

Visceral leishmaniasis is a deadly infectious disease caused by Leishmania donovani, a kinetoplastid parasite for which no licensed vaccine is available. To identify potential vaccine candidates, we systematically identified genes encoding putative cell surface and secreted proteins essential for pa...

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Detalles Bibliográficos
Autores principales: Roberts, Adam, Nagar, Rupa, Brandt, Cordelia, Harcourt, Katherine, Clare, Simon, Ferguson, Michael A. J., Wright, Gavin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239262/
https://www.ncbi.nlm.nih.gov/pubmed/35420475
http://dx.doi.org/10.1128/mbio.00433-22