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Calmodulin Binding Activates Chromobacterium CopC Effector to ADP-Riboxanate Host Apoptotic Caspases

Blocking host cell death is an important virulence strategy employed by many bacterial pathogens. We recently reported that Shigella flexneri inhibits host pyroptosis by delivering a type III secretion system (T3SS) effector OspC3 that catalyzes a novel arginine ADP-riboxanation modification on casp...

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Detalles Bibliográficos
Autores principales: Liu, Yaxin, Zeng, Huan, Hou, Yanjie, Li, Zilin, Li, Lin, Song, Xiaocui, Ding, Jingjin, Shao, Feng, Xu, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239266/
https://www.ncbi.nlm.nih.gov/pubmed/35446120
http://dx.doi.org/10.1128/mbio.00690-22