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Epithelial and Neutrophil Interactions and Coordinated Response to Shigella in a Human Intestinal Enteroid-Neutrophil Coculture Model

Polymorphonuclear neutrophils (PMN) are recruited to the gastrointestinal mucosa in response to inflammation, injury, and infection. Here, we report the development and the characterization of an ex vivo tissue coculture model consisting of human primary intestinal enteroid monolayers and PMN, and a...

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Detalles Bibliográficos
Autores principales: Lemme-Dumit, Jose M., Doucet, Michele, Zachos, Nicholas C., Pasetti, Marcela F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239269/
https://www.ncbi.nlm.nih.gov/pubmed/35652591
http://dx.doi.org/10.1128/mbio.00944-22