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HIV-1 Evolutionary Dynamics under Nonsuppressive Antiretroviral Therapy

Prolonged virologic failure on 2nd-line protease inhibitor (PI)-based antiretroviral therapy (ART) without emergence of major protease mutations is well recognized and provides an opportunity to study within-host evolution in long-term viremic individuals. Using next-generation sequencing and in sil...

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Detalles Bibliográficos
Autores principales: Kemp, Steven A., Charles, Oscar J., Derache, Anne, Smidt, Werner, Martin, Darren P., Iwuji, Collins, Adamson, John, Govender, Katya, de Oliveira, Tulio, Dabis, Francois, Pillay, Deenan, Goldstein, Richard A., Gupta, Ravindra K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239331/
https://www.ncbi.nlm.nih.gov/pubmed/35446121
http://dx.doi.org/10.1128/mbio.00269-22