Midkine-Notch2 Pathway Mediates Excessive Proliferation of Airway Smooth Muscle Cells in Chronic Obstructive Lung Disease

Inflammation-induced proliferation of airway smooth muscle cells (ASMCs) and subsequent airway remodeling is a hallmark of chronic obstructive lung disease (COPD). The role of midkine (MK) in COPD is unclear. In this work, we explored the role of MK-Notch2 signaling in COPD by inhibiting the express...

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Detalles Bibliográficos
Autores principales: Deng, Tang, Huang, Qifeng, Lin, Kaiwen, Qian, Jin, Li, Qi, Li, Lihua, Xu, Shuangqin, Yun, Hongfang, Wang, Hangfei, Wu, Xinxin, Liu, Heng, Jin, Guiyun, Liu, Xiaoran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239375/
https://www.ncbi.nlm.nih.gov/pubmed/35774607
http://dx.doi.org/10.3389/fphar.2022.794952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239375/
https://www.ncbi.nlm.nih.gov/pubmed/35774607
http://dx.doi.org/10.3389/fphar.2022.794952

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