Genomic features underlie the co-option of SVA transposons as cis-regulatory elements in human pluripotent stem cells

Domestication of transposable elements (TEs) into functional cis-regulatory elements is a widespread phenomenon. However, the mechanisms behind why some TEs are co-opted as functional enhancers while others are not are underappreciated. SINE-VNTR-Alus (SVAs) are the youngest group of transposons in...

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Detalles Bibliográficos
Autores principales: Barnada, Samantha M., Isopi, Andrew, Tejada-Martinez, Daniela, Goubert, Clément, Patoori, Sruti, Pagliaroli, Luca, Tracewell, Mason, Trizzino, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239442/
https://www.ncbi.nlm.nih.gov/pubmed/35704668
http://dx.doi.org/10.1371/journal.pgen.1010225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239442/
https://www.ncbi.nlm.nih.gov/pubmed/35704668
http://dx.doi.org/10.1371/journal.pgen.1010225

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