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The distribution of fitness effects of spontaneous mutations in Chlamydomonas reinhardtii inferred using frequency changes under experimental evolution

The distribution of fitness effects (DFE) for new mutations is fundamental for many aspects of population and quantitative genetics. In this study, we have inferred the DFE in the single-celled alga Chlamydomonas reinhardtii by estimating changes in the frequencies of 254 spontaneous mutations under...

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Detalles Bibliográficos
Autores principales: Böndel, Katharina B., Samuels, Toby, Craig, Rory J., Ness, Rob W., Colegrave, Nick, Keightley, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239454/
https://www.ncbi.nlm.nih.gov/pubmed/35704655
http://dx.doi.org/10.1371/journal.pgen.1009840