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The distribution of fitness effects of spontaneous mutations in Chlamydomonas reinhardtii inferred using frequency changes under experimental evolution
The distribution of fitness effects (DFE) for new mutations is fundamental for many aspects of population and quantitative genetics. In this study, we have inferred the DFE in the single-celled alga Chlamydomonas reinhardtii by estimating changes in the frequencies of 254 spontaneous mutations under...
Autores principales: | Böndel, Katharina B., Samuels, Toby, Craig, Rory J., Ness, Rob W., Colegrave, Nick, Keightley, Peter D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239454/ https://www.ncbi.nlm.nih.gov/pubmed/35704655 http://dx.doi.org/10.1371/journal.pgen.1009840 |
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