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Effect of penehyclidine hydrochloride on inflammatory response and oxidative stress in rats with cardiopulmonary bypass related-lung injury

PURPOSE: To investigate the protective effect of penehyclidine hydrochloride (PHC) on cardiopulmonary bypass (CPB)-related lung injury in rats. METHODS: Thirty-six rats were divided into control, CPB and PHC groups. The CPB model was established in CPB and PHC groups. In PHC group, 2-mg/kg PHC was a...

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Detalles Bibliográficos
Autores principales: He, Man, Zhao, Yilin, Li, Shiyong, Luo, Ailin, Chen, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239558/
https://www.ncbi.nlm.nih.gov/pubmed/35766672
http://dx.doi.org/10.1590/acb370406