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Bcar1/p130Cas is essential for ventricular development and neural crest cell remodelling of the cardiac outflow tract

AIMS: The adapter protein p130Cas, encoded by the Bcar1 gene, is a key regulator of cell movement, adhesion, and cell cycle control in diverse cell types. Bcar1 constitutive knockout mice are embryonic lethal by embryonic days (E) 11.5–12.5, but the role of Bcar1 in embryonic development remains unc...

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Detalles Bibliográficos
Autores principales: Mahmoud, Marwa, Evans, Ian, Wisniewski, Laura, Tam, Yuen, Walsh, Claire, Walker-Samuel, Simon, Frankel, Paul, Scambler, Peter, Zachary, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239580/
https://www.ncbi.nlm.nih.gov/pubmed/34270692
http://dx.doi.org/10.1093/cvr/cvab242