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SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies

The outcome of infection is dependent on the ability of viruses to manipulate the infected cell to evade immunity, and the ability of the immune response to overcome this evasion. Understanding this process is key to understanding pathogenesis, genetic risk factors, and both natural and vaccine-indu...

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Detalles Bibliográficos
Autores principales: Fielding, Ceri Alan, Sabberwal, Pragati, Williamson, James C, Greenwood, Edward JD, Crozier, Thomas WM, Zelek, Wioleta, Seow, Jeffrey, Graham, Carl, Huettner, Isabella, Edgeworth, Jonathan D, Price, David A, Morgan, Paul B, Ladell, Kristin, Eberl, Matthias, Humphreys, Ian R, Merrick, Blair, Doores, Katie, Wilson, Sam J, Lehner, Paul J, Wang, Eddie CY, Stanton, Richard J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239683/
https://www.ncbi.nlm.nih.gov/pubmed/35587364
http://dx.doi.org/10.7554/eLife.74489