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All-atom molecular dynamics simulations of Synaptotagmin-SNARE-complexin complexes bridging a vesicle and a flat lipid bilayer
Synaptic vesicles are primed into a state that is ready for fast neurotransmitter release upon Ca(2+)-binding to Synaptotagmin-1. This state likely includes trans-SNARE complexes between the vesicle and plasma membranes that are bound to Synaptotagmin-1 and complexins. However, the nature of this st...
Autores principales: | Rizo, Josep, Sari, Levent, Qi, Yife, Im, Wonpil, Lin, Milo M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239685/ https://www.ncbi.nlm.nih.gov/pubmed/35708237 http://dx.doi.org/10.7554/eLife.76356 |
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