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SARS-CoV-2 ORF8 reshapes the ER through forming mixed disulfides with ER oxidoreductases
The replication machinery of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is closely associated with the endoplasmic reticulum (ER) in host cells. Activation of the unfolded protein response (UPR) is a strategy hijacked by coronavirus to facilitate its replication and suppress ho...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239706/ https://www.ncbi.nlm.nih.gov/pubmed/35792438 http://dx.doi.org/10.1016/j.redox.2022.102388 |