SARS-CoV-2 ORF8 reshapes the ER through forming mixed disulfides with ER oxidoreductases

The replication machinery of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is closely associated with the endoplasmic reticulum (ER) in host cells. Activation of the unfolded protein response (UPR) is a strategy hijacked by coronavirus to facilitate its replication and suppress ho...

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Detalles Bibliográficos
Autores principales: Liu, Ping, Wang, Xi, Sun, Yiwei, Zhao, Hongyu, Cheng, Fang, Wang, Jifeng, Yang, Fuquan, Hu, Junjie, Zhang, Hong, Wang, Chih-chen, Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239706/
https://www.ncbi.nlm.nih.gov/pubmed/35792438
http://dx.doi.org/10.1016/j.redox.2022.102388

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