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Discovering potential interactions between rare diseases and COVID-19 by combining mechanistic models of viral infection with statistical modeling

Recent studies have demonstrated a relevant role of the host genetics in the coronavirus disease 2019 (COVID-19) prognosis. Most of the 7000 rare diseases described to date have a genetic component, typically highly penetrant. However, this vast spectrum of genetic variability remains yet unexplored...

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Detalles Bibliográficos
Autores principales: López-Sánchez, Macarena, Loucera, Carlos, Peña-Chilet, María, Dopazo, Joaquín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239744/
https://www.ncbi.nlm.nih.gov/pubmed/35022696
http://dx.doi.org/10.1093/hmg/ddac007