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A molecular map of long non-coding RNA expression, isoform switching and alternative splicing in osteoarthritis

Osteoarthritis is a prevalent joint disease and a major cause of disability worldwide with no curative therapy. Development of disease-modifying therapies requires a better understanding of the molecular mechanisms underpinning disease. A hallmark of osteoarthritis is cartilage degradation. To defin...

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Detalles Bibliográficos
Autores principales: Katsoula, Georgia, Steinberg, Julia, Tuerlings, Margo, Coutinho de Almeida, Rodrigo, Southam, Lorraine, Swift, Diane, Meulenbelt, Ingrid, Wilkinson, J Mark, Zeggini, Eleftheria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239745/
https://www.ncbi.nlm.nih.gov/pubmed/35088088
http://dx.doi.org/10.1093/hmg/ddac017