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A molecular map of long non-coding RNA expression, isoform switching and alternative splicing in osteoarthritis
Osteoarthritis is a prevalent joint disease and a major cause of disability worldwide with no curative therapy. Development of disease-modifying therapies requires a better understanding of the molecular mechanisms underpinning disease. A hallmark of osteoarthritis is cartilage degradation. To defin...
Autores principales: | Katsoula, Georgia, Steinberg, Julia, Tuerlings, Margo, Coutinho de Almeida, Rodrigo, Southam, Lorraine, Swift, Diane, Meulenbelt, Ingrid, Wilkinson, J Mark, Zeggini, Eleftheria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239745/ https://www.ncbi.nlm.nih.gov/pubmed/35088088 http://dx.doi.org/10.1093/hmg/ddac017 |
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