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The Bridging Effect of Controlled-Release Glial Cell-Derived Neurotrophic Factor Microcapsules within Nerve Conduits on Rat Facial Nerve Regeneration

OBJECTIVES: The study is aimed at exploring the effect of the controlled release of the glial-derived neurotrophic factor (GDNF) on nerve regeneration. METHODS: The PLGA/chitosan composite nerve conduit was used to bridge the dissected trunk of the rat facial nerve. GDNF microcapsules were loaded in...

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Detalles Bibliográficos
Autores principales: Xia, Siwen, Zhang, Mingxing, Li, Meng, Song, Xianmin, Chen, Donghui, Zhu, Minhui, Zheng, Hongliang, Chen, Shicai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239766/
https://www.ncbi.nlm.nih.gov/pubmed/35774850
http://dx.doi.org/10.1155/2022/8942985