Cargando…
Single-nucleotide polymorphisms and the effectiveness of taxane-based chemotherapy in premenopausal breast cancer: a population-based cohort study in Denmark
PURPOSE: Taxane-based chemotherapy is the primary treatment for premenopausal breast cancer. Although being inconsistent, research suggests that variant alleles alter pharmacokinetics through reduced function of OATP transporters (limiting hepatic uptake), CYP-450 enzymes (hampering drug metabolism)...
Autores principales: | Hjorth, Cathrine F., Damkier, Per, Stage, Tore B., Feddersen, Søren, Hamilton-Dutoit, Stephen, Rørth, Mikael, Ejlertsen, Bent, Lash, Timothy L., Ahern, Thomas P., Sørensen, Henrik T., Cronin-Fenton, Deirdre |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239972/ https://www.ncbi.nlm.nih.gov/pubmed/35501422 http://dx.doi.org/10.1007/s10549-022-06596-2 |
Ejemplares similares
-
The impact of single nucleotide polymorphisms on return-to-work after taxane-based chemotherapy in breast cancer
por: Hjorth, Cathrine F., et al.
Publicado: (2023) -
Socioeconomic position and prognosis in premenopausal breast cancer: a population-based cohort study in Denmark
por: Hjorth, Cathrine Fonnesbech, et al.
Publicado: (2021) -
Correction: Socioeconomic position and prognosis in premenopausal breast cancer: a population-based cohort study in Denmark
por: Hjorth, Cathrine Fonnesbech, et al.
Publicado: (2023) -
Cohort Profile: the Predictors of Breast Cancer Recurrence (ProBe CaRE) Premenopausal Breast Cancer Cohort Study in Denmark
por: Collin, Lindsay J, et al.
Publicado: (2018) -
Challenges in translating endpoints from trials to observational cohort studies in oncology
por: Ording, Anne Gulbech, et al.
Publicado: (2016)