Cargando…

Structural basis for mitoguardin-2 mediated lipid transport at ER-mitochondrial membrane contact sites

The endoplasmic reticulum (ER)-mitochondria contact site (ERMCS) is crucial for exchanging biological molecules such as phospholipids and Ca(2+) ions between these organelles. Mitoguardin-2 (MIGA2), a mitochondrial outer membrane protein, forms the ERMCS in higher eukaryotic cells. Here, we report t...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Hyunwoo, Lee, Seowhang, Jun, Youngsoo, Lee, Changwook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239997/
https://www.ncbi.nlm.nih.gov/pubmed/35764626
http://dx.doi.org/10.1038/s41467-022-31462-6