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A degradative to secretory autophagy switch mediates mitochondria clearance in the absence of the mATG8-conjugation machinery

PINK1-Parkin mediated mitophagy, a selective form of autophagy, represents one of the most important mechanisms in mitochondrial quality control (MQC) via the clearance of damaged mitochondria. Although it is well known that the conjugation of mammalian ATG8s (mATG8s) to phosphatidylethanolamine (PE...

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Detalles Bibliográficos
Autores principales: Tan, Hayden Weng Siong, Lu, Guang, Dong, Han, Cho, Yik-Lam, Natalia, Auginia, Wang, Liming, Chan, Charlene, Kappei, Dennis, Taneja, Reshma, Ling, Shuo-Chien, Shao, Huilin, Tsai, Shih-Yin, Ding, Wen-Xing, Shen, Han-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240011/
https://www.ncbi.nlm.nih.gov/pubmed/35764633
http://dx.doi.org/10.1038/s41467-022-31213-7