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Lsm7 phase-separated condensates trigger stress granule formation

Stress granules (SGs) are non-membranous organelles facilitating stress responses and linking the pathology of age-related diseases. In a genome-wide imaging-based phenomic screen, we identify Pab1 co-localizing proteins under 2-deoxy-D-glucose (2-DG) induced stress in Saccharomyces cerevisiae. We f...

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Detalles Bibliográficos
Autores principales: Lindström, Michelle, Chen, Lihua, Jiang, Shan, Zhang, Dan, Gao, Yuan, Zheng, Ju, Hao, Xinxin, Yang, Xiaoxue, Kabbinale, Arpitha, Thoma, Johannes, Metzger, Lisa C., Zhang, Deyuan Y., Zhu, Xuefeng, Liu, Huisheng, Gustafsson, Claes M., Burmann, Björn M., Winderickx, Joris, Sunnerhagen, Per, Liu, Beidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240020/
https://www.ncbi.nlm.nih.gov/pubmed/35764627
http://dx.doi.org/10.1038/s41467-022-31282-8