The impact of rare germline variants on human somatic mutation processes

Somatic mutations are an inevitable component of ageing and the most important cause of cancer. The rates and types of somatic mutation vary across individuals, but relatively few inherited influences on mutation processes are known. We perform a gene-based rare variant association study with divers...

Descripción completa

Detalles Bibliográficos
Autores principales: Vali-Pour, Mischan, Park, Solip, Espinosa-Carrasco, Jose, Ortiz-Martínez, Daniel, Lehner, Ben, Supek, Fran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240060/
https://www.ncbi.nlm.nih.gov/pubmed/35764656
http://dx.doi.org/10.1038/s41467-022-31483-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240060/
https://www.ncbi.nlm.nih.gov/pubmed/35764656
http://dx.doi.org/10.1038/s41467-022-31483-1

Ejemplares similares