Cargando…

Pancreatic α and β cells are globally phase-locked

The Ca(2+) modulated pulsatile glucagon and insulin secretions by pancreatic α and β cells play a crucial role in glucose homeostasis. However, how α and β cells coordinate to produce various Ca(2+) oscillation patterns is still elusive. Using a microfluidic device and transgenic mice, we recorded C...

Descripción completa

Detalles Bibliográficos
Autores principales: Ren, Huixia, Li, Yanjun, Han, Chengsheng, Yu, Yi, Shi, Bowen, Peng, Xiaohong, Zhang, Tianming, Wu, Shufang, Yang, Xiaojing, Kim, Sneppen, Chen, Liangyi, Tang, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240067/
https://www.ncbi.nlm.nih.gov/pubmed/35764654
http://dx.doi.org/10.1038/s41467-022-31373-6