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Pancreatic α and β cells are globally phase-locked
The Ca(2+) modulated pulsatile glucagon and insulin secretions by pancreatic α and β cells play a crucial role in glucose homeostasis. However, how α and β cells coordinate to produce various Ca(2+) oscillation patterns is still elusive. Using a microfluidic device and transgenic mice, we recorded C...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240067/ https://www.ncbi.nlm.nih.gov/pubmed/35764654 http://dx.doi.org/10.1038/s41467-022-31373-6 |