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A model-specific simplification of the Mouse Grimace Scale based on the pain response of intraperitoneal CCl(4) injections

Despite its long establishment and applicability in mice pain detection, the Mouse Grimace Scale still seems to be underused in acute pain detection during chronic experiments. However, broadening its applicability can identify possible refinement approaches such as cumulative severity and habituati...

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Detalles Bibliográficos
Autores principales: Ernst, Lisa, Bruch, Stefan, Kopaczka, Marcin, Merhof, Dorit, Bleich, André, Tolba, René H., Talbot, Steven R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240072/
https://www.ncbi.nlm.nih.gov/pubmed/35764784
http://dx.doi.org/10.1038/s41598-022-14852-0