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A model-specific simplification of the Mouse Grimace Scale based on the pain response of intraperitoneal CCl(4) injections
Despite its long establishment and applicability in mice pain detection, the Mouse Grimace Scale still seems to be underused in acute pain detection during chronic experiments. However, broadening its applicability can identify possible refinement approaches such as cumulative severity and habituati...
Autores principales: | Ernst, Lisa, Bruch, Stefan, Kopaczka, Marcin, Merhof, Dorit, Bleich, André, Tolba, René H., Talbot, Steven R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240072/ https://www.ncbi.nlm.nih.gov/pubmed/35764784 http://dx.doi.org/10.1038/s41598-022-14852-0 |
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