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Pharmacologic Inhibition of Histone Deacetylase 6 Prevents the Progression of Chlorhexidine Gluconate-Induced Peritoneal Fibrosis by Blockade of M2 Macrophage Polarization

Peritoneal fibrosis contributes to ultrafiltration failure in peritoneal dialysis (PD) patients and thus restricts the wide application of PD in clinic. Recently we have demonstrated that histone deacetylase 6 (HDAC6) is critically implicated in high glucose peritoneal dialysis fluid (HG-PDF) induce...

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Detalles Bibliográficos
Autores principales: Shi, Yingfeng, Li, Jinqing, Chen, Hui, Hu, Yan, Tang, Lunxian, Zhou, Xun, Tao, Min, Lv, Zexin, Chen, Si, Qiu, Andong, Liu, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240186/
https://www.ncbi.nlm.nih.gov/pubmed/35784347
http://dx.doi.org/10.3389/fimmu.2022.899140