Urolithin A Attenuates Hyperuricemic Nephropathy in Fructose-Fed Mice by Impairing STING-NLRP3 Axis-Mediated Inflammatory Response via Restoration of Parkin-Dependent Mitophagy

Urolithin A (UroA) is one of the primary intestinal metabolites of ellagitannins, showing translational potential as a nutritional intervention in humans. Mounting evidence suggests that fructose consumption contributes to the progression of chronic kidney disease (CKD) that manifests in hyperuricem...

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Detalles Bibliográficos
Autores principales: Zhang, Cong, Song, Yingying, Chen, Liang, Chen, Peng, Yuan, Ming, Meng, Yan, Wang, Qi, Zheng, Guohua, Qiu, Zhenpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240289/
https://www.ncbi.nlm.nih.gov/pubmed/35784701
http://dx.doi.org/10.3389/fphar.2022.907209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240289/
https://www.ncbi.nlm.nih.gov/pubmed/35784701
http://dx.doi.org/10.3389/fphar.2022.907209

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