As in Real Estate, Location Matters: Cellular Expression of Complement Varies Between Macular and Peripheral Regions of the Retina and Supporting Tissues

The cellular events that dictate the initiation of the complement pathway in ocular degeneration, such as age-related macular degeneration (AMD), is poorly understood. Using gene expression analysis (single cell and bulk), mass spectrometry, and immunohistochemistry, we dissected the role of multipl...

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Detalles Bibliográficos
Autores principales: Zauhar, Randy, Biber, Josef, Jabri, Yassin, Kim, Mijin, Hu, Jian, Kaplan, Lew, Pfaller, Anna M., Schäfer, Nicole, Enzmann, Volker, Schlötzer-Schrehardt, Ursula, Straub, Tobias, Hauck, Stefanie M., Gamlin, Paul D., McFerrin, Michael B., Messinger, Jeffrey, Strang, Christianne E., Curcio, Christine A., Dana, Nicholas, Pauly, Diana, Grosche, Antje, Li, Mingyao, Stambolian, Dwight
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240314/
https://www.ncbi.nlm.nih.gov/pubmed/35784369
http://dx.doi.org/10.3389/fimmu.2022.895519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240314/
https://www.ncbi.nlm.nih.gov/pubmed/35784369
http://dx.doi.org/10.3389/fimmu.2022.895519

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