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As in Real Estate, Location Matters: Cellular Expression of Complement Varies Between Macular and Peripheral Regions of the Retina and Supporting Tissues
The cellular events that dictate the initiation of the complement pathway in ocular degeneration, such as age-related macular degeneration (AMD), is poorly understood. Using gene expression analysis (single cell and bulk), mass spectrometry, and immunohistochemistry, we dissected the role of multipl...
Autores principales: | Zauhar, Randy, Biber, Josef, Jabri, Yassin, Kim, Mijin, Hu, Jian, Kaplan, Lew, Pfaller, Anna M., Schäfer, Nicole, Enzmann, Volker, Schlötzer-Schrehardt, Ursula, Straub, Tobias, Hauck, Stefanie M., Gamlin, Paul D., McFerrin, Michael B., Messinger, Jeffrey, Strang, Christianne E., Curcio, Christine A., Dana, Nicholas, Pauly, Diana, Grosche, Antje, Li, Mingyao, Stambolian, Dwight |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240314/ https://www.ncbi.nlm.nih.gov/pubmed/35784369 http://dx.doi.org/10.3389/fimmu.2022.895519 |
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