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Antisense Oligonucleotide-Based Therapy on miR-181a-5p Alleviates Cartilage Degradation of Temporomandibular Joint Osteoarthritis via Promoting SIRT1

Temporomandibular joint osteoarthritis (TMJOA) condylar cartilage degeneration and abnormal subchondral bone pathological remodeling induce pain and joint dysfunction, and cartilage degeneration is considered irreversible. Very few therapeutic approaches are administrated in practice. Nucleotides ha...

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Detalles Bibliográficos
Autores principales: Qi, Hexu, Zhao, Zhenxing, Xu, Lin, Zhang, Yue, Li, Yifei, Xiao, Li, Li, Yu, Zhao, Zhihe, Fang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240346/
https://www.ncbi.nlm.nih.gov/pubmed/35784690
http://dx.doi.org/10.3389/fphar.2022.898334