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Biochemical Characterization and Synthetic Application of WciN and Its Mutants From Streptococcus pneumoniae Serotype 6B

The biochemical properties of α-1,3-galactosyltransferase WciN from Streptococcus pneumoniae serotype 6B were systemically characterized with the chemically synthesized Glcα-PP-(CH(2))(11)-OPh as an acceptor substrate. The in vitro site-directed mutation of D38 and A150 residues of WciN was further...

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Detalles Bibliográficos
Autores principales: Gong, Wei, Liang, Min, Zhao, Jielin, Wang, Hong, Chen, Zonggang, Wang, Fengshan, Gu, Guofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240355/
https://www.ncbi.nlm.nih.gov/pubmed/35783203
http://dx.doi.org/10.3389/fchem.2022.914698