Effects of Hydroxyurea on Skeletal Muscle Energetics and Function in a Mildly Anemic Mouse Model

Hydroxyurea (HU) is a ribonucleotide reductase inhibitor most commonly used as a therapeutic agent in sickle cell disease (SCD) with the aim of reducing the risk of vaso-occlusion and improving oxygen transport to tissues. Previous studies suggest that HU may be even beneficial in mild anemia. Howev...

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Detalles Bibliográficos
Autores principales: Michel, Constance P., Messonnier, Laurent A., Giannesini, Benoit, Chatel, Benjamin, Vilmen, Christophe, Le Fur, Yann, Bendahan, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240423/
https://www.ncbi.nlm.nih.gov/pubmed/35784862
http://dx.doi.org/10.3389/fphys.2022.915640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240423/
https://www.ncbi.nlm.nih.gov/pubmed/35784862
http://dx.doi.org/10.3389/fphys.2022.915640

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