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PD-L1 Regulates Platelet Activation and Thrombosis via Caspase-3/GSDME Pathway

Platelets play a central role in hemostasis and thrombosis, regulating the occurrence and development of thrombotic diseases, including ischemic stroke. Programmed death ligand 1 (PD-L1) has recently been detected in platelet, while the function of PD-L1 in platelets remain elusive. Our data reveal...

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Detalles Bibliográficos
Autores principales: Li, Yulong, Xin, Guang, Li, Shiyi, Dong, Yuman, Zhu, Yuda, Yu, Xiuxian, Wan, Chengyu, Li, Fan, Wei, Zeliang, Wang, Yilan, Zhang, Kun, Chen, Qingqiu, Niu, Hai, Huang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240427/
https://www.ncbi.nlm.nih.gov/pubmed/35784685
http://dx.doi.org/10.3389/fphar.2022.921414