RecQ Helicase Somatic Alterations in Cancer

Named the “caretakers” of the genome, RecQ helicases function in several pathways to maintain genomic stability and repair DNA. This highly conserved family of enzymes consist of five different proteins in humans: RECQL1, BLM, WRN, RECQL4, and RECQL5. Biallelic germline mutations in BLM, WRN, and RE...

Descripción completa

Detalles Bibliográficos
Autores principales: Thakkar, Megha K., Lee, Jamie, Meyer, Stefan, Chang, Vivian Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240438/
https://www.ncbi.nlm.nih.gov/pubmed/35782872
http://dx.doi.org/10.3389/fmolb.2022.887758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240438/
https://www.ncbi.nlm.nih.gov/pubmed/35782872
http://dx.doi.org/10.3389/fmolb.2022.887758

Ejemplares similares