Influence of Gender, Body Mass Index, and Age on the Pharmacokinetics of Itraconazole in Healthy Subjects: Non-Compartmental Versus Compartmental Analysis

Itraconazole is a triazole antifungal agent with highly variable pharmacokinetics, with not yet fully identified factors as the source of this variability. Our study aimed to examine the influence of body mass index, gender, and age on the first dose pharmacokinetics of itraconazole in healthy subje...

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Detalles Bibliográficos
Autores principales: Miljković, Milijana N., Rančić, Nemanja, Kovačević, Aleksandra, Cikota-Aleksić, Bojana, Skadrić, Ivan, Jaćević, Vesna, Mikov, Momir, Dragojević-Simić, Viktorija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240599/
https://www.ncbi.nlm.nih.gov/pubmed/35784683
http://dx.doi.org/10.3389/fphar.2022.796336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240599/
https://www.ncbi.nlm.nih.gov/pubmed/35784683
http://dx.doi.org/10.3389/fphar.2022.796336

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