Optimized NGFR-derived hinges for rapid and efficient enrichment and detection of CAR T cells in vitro and in vivo

Chimeric antigen receptor (CAR) T cell therapy has demonstrated unprecedented success with high remission rates for heavily pretreated patients with hematological malignancies. The hinge connecting the extracellular antigen recognition unit to the transmembrane domain provides the length and flexibi...

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Detalles Bibliográficos
Autores principales: Bister, A., Ibach, T., Haist, C., Gerhorst, G., Smorra, D., Soldierer, M., Roellecke, K., Wagenmann, M., Scheckenbach, K., Gattermann, N., Wiek, C., Hanenberg, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240717/
https://www.ncbi.nlm.nih.gov/pubmed/35795096
http://dx.doi.org/10.1016/j.omto.2022.05.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240717/
https://www.ncbi.nlm.nih.gov/pubmed/35795096
http://dx.doi.org/10.1016/j.omto.2022.05.012

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