m4C DNA methylation regulates biosynthesis of daptomycin in Streptomyces roseosporus L30

Despite numerous studies on transcriptional level regulation by single genes in drug producing Actinomyces, the global regulation based on epigenetic modification is not well explored. N4-methylcytosine (m4C), an abundant epigenetic marker in Actinomycetes’ genome, but its regulatory mechanism remai...

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Detalles Bibliográficos
Autores principales: Fang, Jiao-Le, Gao, Wen-Li, Xu, Wei-Feng, Lyu, Zhong-Yuan, Ma, Lie, Luo, Shuai, Chen, Xin-Ai, Mao, Xu-Ming, Li, Yong-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240718/
https://www.ncbi.nlm.nih.gov/pubmed/35801092
http://dx.doi.org/10.1016/j.synbio.2022.06.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240718/
https://www.ncbi.nlm.nih.gov/pubmed/35801092
http://dx.doi.org/10.1016/j.synbio.2022.06.001

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