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Memory T Cell Subpopulations as Early Predictors of Remission to Vedolizumab in Ulcerative Colitis

BACKGROUND: Vedolizumab is a humanized monoclonal antibody targeting the α(4)β(7) integrin used for the treatment of ulcerative colitis. Few biomarkers related to vedolizumab response have been identified. The aim of this work was to assess whether baseline circulating CD4(+) and CD8(+) memory T-lym...

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Detalles Bibliográficos
Autores principales: Gonzalez-Vivo, Maria, Lund Tiirikainen, Minna K., Andreu, Montserrat, Fernandez-Clotet, Agnes, López-García, Alicia, Murciano Gonzalo, Francisca, Abril Rodriguez, Lourdes, de Jesús-Gil, Carmen, Ruiz-Romeu, Ester, Sans-de San Nicolàs, Lídia, Santamaria-Babí, Lluis F., Márquez-Mosquera, Lucía
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240758/
https://www.ncbi.nlm.nih.gov/pubmed/35783609
http://dx.doi.org/10.3389/fmed.2022.837294