Cargando…

The Allelic Variant A391T of Metal Ion Transporter ZIP8 (SLC39A8) Leads to Hypotension and Enhanced Insulin Resistance

The metal ion transporter ZIP8 (SLC39A8) mediates cellular uptake of vital divalent metal ions. Genome-wide association studies (GWAS) showed that the single-nucleotide polymorphism (SNP) variant A391T (rs13107325) is associated with numerous human traits, including reduced arterial blood pressure,...

Descripción completa

Detalles Bibliográficos
Autores principales: Verouti, Sophia N., Pujol-Giménez, Jonai, Bermudez-Lekerika, Paola, Scherler, Laeticia, Bhardwaj, Rajesh, Thomas, Aurélien, Lenglet, Sébastien, Siegrist, Mark, Hofstetter, Willy, Fuster, Daniel G., Hediger, Matthias A., Escher, Geneviève, Vogt, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240775/
https://www.ncbi.nlm.nih.gov/pubmed/35784893
http://dx.doi.org/10.3389/fphys.2022.912277