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The Allelic Variant A391T of Metal Ion Transporter ZIP8 (SLC39A8) Leads to Hypotension and Enhanced Insulin Resistance
The metal ion transporter ZIP8 (SLC39A8) mediates cellular uptake of vital divalent metal ions. Genome-wide association studies (GWAS) showed that the single-nucleotide polymorphism (SNP) variant A391T (rs13107325) is associated with numerous human traits, including reduced arterial blood pressure,...
Autores principales: | Verouti, Sophia N., Pujol-Giménez, Jonai, Bermudez-Lekerika, Paola, Scherler, Laeticia, Bhardwaj, Rajesh, Thomas, Aurélien, Lenglet, Sébastien, Siegrist, Mark, Hofstetter, Willy, Fuster, Daniel G., Hediger, Matthias A., Escher, Geneviève, Vogt, Bruno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240775/ https://www.ncbi.nlm.nih.gov/pubmed/35784893 http://dx.doi.org/10.3389/fphys.2022.912277 |
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